Alumi Laparoscopic Discussion Board

What is your opinion about ICG
Discussion in 'All Categories' started by Dr R K Mishra - May 16th, 2016 2:33 pm.
Dr R K Mishra
Dr R K Mishra
ICG has been demonstrated to be used during laparoscopic cholecystectomy to visualize CBD. Should we start using in in our hospital and should we give instruction and training to be used by our alumni as well.

Identification of the CBD and CD using a low dose of ICG and the NIR camera was both faster and more frequent compared with conventional laparoscopic images during elective laparoscopic cholecystectomy.

Indocyanine Green for Injection USP is a sterile, lyophilized green powder containing 25 mg of Indocyanine Green with no more than 5% sodium iodide. Indocyanine Green for Injection USP is dissolved using Sterile Water for Injection, and is to be administered intravenously.

Please discuss this topic.
re: What is your opinion about ICG by Dr Md Azhar - May 16th, 2016 2:37 pm
Dr Md Azhar
Dr Md Azhar
What is the technique of Injecting and visualizing ICG during Laparoscopic Cholecystectomy. If application is simple then why not, We should try this.
re: What is your opinion about ICG by Dr Poonam Sharma - May 17th, 2016 12:17 am
Dr Poonam Sharma
Dr Poonam Sharma
Is there any role of ICG in gynecological laparoscopy.
re: What is your opinion about ICG by Dr. Sangeeta Saxena - May 17th, 2016 12:20 am
Dr. Sangeeta Saxena
Dr. Sangeeta Saxena
Hi Everyone!
There is use ICG in cervical or endometrial cancer with the goal to provide details during complete lymphadenectomy, particularly the rate of lymphedema, while also increasing the detection of small tumor deposits in the node. There has been increasing interest in the use of fluorescent dies such as indocyanine green (ICG) for this purpose in gynecological practice.
re: What is your opinion about ICG by Dr Vipul Rai - May 17th, 2016 5:53 am
Dr Vipul Rai
Dr Vipul Rai
Indocyanine green has been used for decades in ophthalmology for imaging retinal blood vessels, that is, in retinal angiography. However, fluorescein operating in visual wavelengths has been much more popular in retinal angiography partly because it is visible without any electronic cameras.
re: What is your opinion about ICG by Dr R K Mishra - May 17th, 2016 6:13 am
Dr R K Mishra
Dr R K Mishra
Indocyanine green dye was developed for near-infrared (NIR) photography by the Kodak Research Laboratories in 1955 and was approved for clinical use already in 1956. The principle of fluorescence imaging used in ICG angiography (ICGA) is simple: illuminate the tissue of interest with light at the excitation wavelength (about 750 to 800 nm) while observing it at longer emission wavelengths over 800 nm.

Recently new successful medical applications, mainly in surgery, have been introduced. Some of the ICG’s subexcellent properties provide further challenges to research and engineering development:
ICG is very recent in many applications such as cancer treatment, reconstructive surgery, and even in cholecystectomy, .ICG does not have any known metabolites, and it is fast extracted by the liver into bile juice. The transport is done by a protein called glutathione S-transferase without modification.

The typical dye concentrations used is in the range of 20–25 mg/mL of ICG applied by injection into a peripheral arm vein. For studies of hepatic function an intravenous injection dose is calculated on the basis of 0.5 mg/kg of body weight. In cardiac output and blood volume monitoring the total dose of dye injected should be kept below 2 mg/kg. No significant toxic effects have been observed in humans with the high dose of 5 mg/kg of body weight.
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