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Discussion in 'All Categories' started by Sanmay - Dec 13th, 2023 11:57 am.
I am suffering from acromegaly. What are the available treatment options for acromegaly?
re: Acromegaly by Dr. B. S. Bhalla - Dec 13th, 2023 11:58 am
Dr. B. S. Bhalla
Dr. B. S. Bhalla
Acromegaly is a rare hormonal disorder that occurs when the pituitary gland produces excessive growth hormone (GH). The goal of treatment is to reduce GH levels and control the symptoms associated with acromegaly. Here are some common treatment options:

Surgery: Transsphenoidal surgery is often the first-line treatment for acromegaly. This procedure involves removing the tumor through the nasal cavity, avoiding external incisions. However, complete removal may not always be possible.

Medication: Medications are commonly used to lower GH levels and reduce tumor size. Somatostatin analogs (e.g., octreotide, lanreotide) can help control GH secretion. Dopamine agonists (e.g., cabergoline) may be used in some cases. Pegvisomant, a growth hormone receptor antagonist, is another option.

Radiation Therapy: Radiation therapy may be considered when surgery and medications are not sufficient. It aims to shrink or control tumor growth. Different types of radiation, such as conventional external beam radiation or stereotactic radiosurgery, may be used.

Combination Therapy: Sometimes, a combination of surgery, medication, and radiation therapy may be recommended to effectively manage acromegaly.

Regular Monitoring: After treatment, regular monitoring is essential to assess hormone levels, monitor tumor size, and adjust treatment as needed.
re: Acromegaly by Arun - Jan 14th, 2024 11:49 am
Are there medications that can help manage acromegaly symptoms?
re: Acromegaly by Dr. Bishal - Jan 14th, 2024 11:51 am
Dr. Bishal
Dr. Bishal
Yes, medications are often used to help manage symptoms of acromegaly. Acromegaly is a disorder caused by excess growth hormone production, usually due to a noncancerous tumor of the pituitary gland. The main goals of treatment are to reduce the production of growth hormone, shrink the tumor, and alleviate symptoms.

Somatostatin Analogues (SSAs): These drugs, such as octreotide and lanreotide, mimic the action of somatostatin, a hormone that inhibits the release of growth hormone. By using SSAs, the excess production of growth hormone can be controlled. These medications are usually administered as injections.

Dopamine Agonists: Cabergoline is a dopamine agonist that may be used in some cases to help lower growth hormone levels. However, it is not as effective as somatostatin analogues and is typically considered as an alternative or adjunctive therapy.

Growth Hormone Receptor Antagonists: Pegvisomant is a medication that blocks the action of growth hormone by binding to its receptor. It is usually used in cases where somatostatin analogues alone are not sufficient.

Surgery: In some cases, surgical removal of the tumor (transsphenoidal surgery) may be recommended, especially if the tumor is causing compression of surrounding structures. Surgery is often considered when medications alone are not effective or when there are complications.

Radiation Therapy: In cases where surgery is not an option or not successful, radiation therapy may be considered to shrink the tumor and control growth hormone production. This is usually a more long-term treatment option.
re: Acromegaly by Dheeraj - Apr 10th, 2024 10:03 am
What are the potential complications of acromegaly, and how can they be prevented or managed?
re: Acromegaly by Dr. Rishi - Apr 10th, 2024 10:04 am
Dr. Rishi
Dr. Rishi
Acromegaly can lead to several complications if not properly managed. Some potential complications include:

Cardiovascular issues: Acromegaly can increase the risk of hypertension, heart disease, and cardiomyopathy. It's important to monitor blood pressure and manage cardiovascular risk factors such as high cholesterol and diabetes.

Joint problems: The excess growth hormone can lead to joint pain, arthritis, and in severe cases, joint deformities. Physical therapy, pain management, and joint protection techniques can help manage these issues.

Sleep apnea: Enlargement of tissues in the throat can cause obstructive sleep apnea. Continuous positive airway pressure (CPAP) therapy is often used to manage this condition.

Diabetes: Acromegaly can increase the risk of developing diabetes. Monitoring blood sugar levels and following a healthy diet and exercise regimen can help manage this risk.

Vision problems: Tumor growth in the pituitary gland can lead to visual disturbances or even loss of vision. Regular eye exams are important for early detection and management.

Increased risk of certain cancers: People with acromegaly may have a slightly higher risk of developing certain types of cancer, such as colorectal cancer. Regular screenings can help detect cancer early.

Psychological effects: Living with a chronic condition like acromegaly can lead to psychological issues such as anxiety and depression. Counseling or therapy can be helpful in managing these issues.
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