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problem to conceive
Discussion in 'All Categories' started by vishal - Apr 5th, 2013 5:16 am.
I have adaughter 10 years old. my wifes age is 35 wife got 3 miscorage in last 4 years . now problem in conceiving.
re: problem to conceive by Dr J S Chowhan - Apr 5th, 2013 10:06 am
Dr J S Chowhan
Dr J S Chowhan
Dear Mr Vishal

You need to get examined by a good infertility expert to find out the cause of repeated abortion.

If a miscarriage happens throughout the second trimester of pregnancy (between weeks 14 and 26), it is usually the consequence of a basic health condition from the mother.

First trimester miscarriages

Most first trimester miscarriages are caused by difficulties with the chromosomes in the foetus.
Chromosome problems

Chromosomes are blocks of DNA. They have a detailed set of instructions that control an array of factors, from what sort of cells with the body develop to what colour eyes an infant could have. For a pregnancy to achieve success, a foetus will need to have 46 chromosomes altogether:

23 are from the father sperm
23 originate from the mother egg

Sometimes, something can go wrong on the reason for conception along with the foetus receives way too many you are not enough chromosomes. The causes because of this in many cases are unclear, however it implies that the foetus will not be able to formulate normally, producing a miscarriage. It is estimated that around 2 / 3 of early miscarriages are related to chromosome abnormalities.
Placental problems

The placenta may be the organ that links the mother blood flow to her baby. When there is an issue with the roll-out of the placenta it can also lead to a miscarriage.

Risk factors

An early on miscarriage could happen accidentally. However, there are lots of known risks which improve the probability of problems occurring.


One of the most important risk factor for miscarriage will be the age of mom:
Ladies under 30, 10 percent pregnancies can easily in miscarriage.
In females aged 35-39, approximately 2 in 10 pregnancies can easily in miscarriage. Ladies over 45, over fifty percent of most pregnancies can finish in miscarriage.

Other risk factors

Other risks for having a miscarriage include:
smoking while pregnant
drug misuse during pregnancy
drinking more than 200mg of caffeine every day: one mug of tea contains around 75 mg of caffeine, then one mug of instant coffee contains around 100 mg of caffeine.

drinking greater than two units of alcohol weekly: one unit is half a pint of bitter or ordinary strength lager, a tiny drop of vino or perhaps a 25ml measure of spirits.

Second trimester miscarriages

Long-term health issues

There are several long-term health issues that could raise the risk of creating a miscarriage. These are generally:
severe hypertension
kidney disease
an overactive thyroid gland
an underactive hypothyroid
coeliac disease


There are a few infections that could improve the likelihood of developing a miscarriage. Included in this are:

a bacterial infection with the vagina called bacterial vaginosis


sexually transmitted infection including chlamydia, gonorrhoea and syphilis


Some medicines can also increase potential risk of miscarriage:
non steroidal anti inflammatory drugs
On medicines while pregnant. To make sure that medicine is protected in pregnancy, look for using your doctor, midwife or pharmacist before it.

Antibodies are proteins which can be created by the body defence mechanism to fight infection.

Some ladies who have experienced a variety of miscarriages back to back have a greater than usual level of an antibody called antiphospholipid in their blood. The aPL antibodies are known to cause thrombus. These blood clots can block the provision of blood for the foetus, which could cause a miscarriage. Using a high number of aPL antibodies in your blood is known as Hughes syndrome. On Hughes syndrome.

Womb structure

Problems and abnormalities together with the womb can also lead to second trimester miscarriages. Potential problems with all the structure in the womb include:

non-cancerous growths within the womb called fibroids
scarring on the surface of the womb
Weakened cervix

Sometimes, the muscles from the cervix neck with the womb are weaker than usual. This is called a weakened cervix or cervical incompetence. A weakened cervix are closely related to a previous damage to the therapy lamp, or could have been something you had been born with. The pc muscle weakness may cause the cervix to start prematurily . while pregnant, resulting in a miscarriage.


Prolactin is often a hormone that is produced in pregnancy. Prolactin really helps to prepare the breast tissue for breastfeeding. Sometimes, ladies have the next step of prolactin of their body than usual. This is whats called hyperprolactinaemia. Some limited evidence suggests that hyperprolactinaemia may be related to a heightened risk of miscarriage.


Pcos (PCOS) can be a condition the location where the ovaries are bigger than normal. It can lead to hormonal imbalances in the womb. Polycystic ovary syndrome is known as a number one reason for infertility. There is some evidence to point out that it may be also connected to an elevated risk of miscarriage in females who are still fertile. However, the actual role that pcos plays in miscarriages is unclear.

With regard

J S Chowhan
World Laparoscopy Hospital
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