|Discussion in 'All Categories' started by Rathipriya - Jul 3rd, 2012 2:14 am.|
|Now, I am 31 years.I am having bilateral ploycystic ovaries for past 6 months. I am taking glycomet 250mg twice per day. Periods are regular (31 to 34 days). My husband's sperm count averagely 30 million per ml and mobility 40%. What should i do to get pergnant.|
re: Pergnancy by Dr J S Chowhan - Jul 5th, 2012 11:59 am
Dr J S Chowhan
Polycystic ovarian disease is a common problem found in females of reproductive age group and it as a major cause of infertility. One of the leading biochemical features of polycystic ovary syndrome which does not allow pregnancy to happen is insulin resistance combined with compensatory hyperinsulinemia elevated fasting insulin shots levels. In many patient who want to get pregnant hyperinsulinemia produces the hyperandrogenism of pcos by increasing ovarian androgen production, particularly testosterone and by decreasing the serum sex hormone binding globulin concentration.
Our prime amounts of androgenic hormones hinder the pituitary ovarian axis, leading to increased LH levels, anovulation, amenorrhea, recurrent pregnancy loss, and infertility. Hyperinsulinemia has also been associated high blood pressure and increased clot formation and appearance to be a major risk factor to add mass to heart disease, stroke and type II diabetes.
For women in the reproductive age groups, pcos is a serious, standard reason for infertility, because of the endocrine abnormalities which accompany elevated insulin levels. There is increasing evidence this endocrine abnormality can be reversed by treatment with widely available standard medications that are leading medicines used in america for the treatment of adult onset diabetes, metformin, Glucophage 500 or 850 mg three times per day or 1000mg twice daily with meals, pioglitazone Actos 15-30 mg daily, rosiglitazone, Avandia 4-8 mg once daily or perhaps a combination of these medications.
Ovarian drilling can be performed at the time of laparoscopy. A laser fibre or electrosurgical needle can be used to puncture the ovary 10-12 times. Laser hair removal results in a dramatic cut in male hormones within days. Studies have shown that as much as 80% may benefit from such treatment. Lots who didn't ovulate with letrozole or metformin therapy will respond when rechallenged with one of these medications after ovarian drilling. Interestingly, women during these studies who're smokers, rarely responded to the drilling procedure. Negative effects are rare, but may lead to adhesion formation or ovarian failure when the procedure is performed by an inexperienced surgeon.
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