|Discussion in 'All Categories' started by p sridhar - Jul 22nd, 2012 11:59 am.|
my father in law is recently operated for knee replacement but now he is facing problem of low appetite and not able recovery.So he was taken for scaning and it is reported that he is having the problem of gallstone having size of 12mm.So please suggest and advise for action to be taken immediately or later on.
re: gallbladder stone problem by Dr M CGupta - Jul 24th, 2012 1:23 pm
Dr M CGupta
|Dear Mr Sridhar
If your father has the problem with the gallbladder stone it ought to be removed. In many from the popullation bases studies it is confirmed that gallstones are an important risk factor for all three subsites of biliary cancer, specially when complicated by chronic cholecystitis.
The most common risk factor for gallbladder cancer is gallstones, that are present in 75%-90% of gallbladder cancer cases
The size of the gallstones plays a role in the chance of developing of gallbladder cancer. Gallbladders containing gallstones that are more than 3 cm in diameter have a 10-fold and the higher chances for developing malignancy compared to those containing gallstones which are 1 cm across. Causality is difficult to determine, but other chronic inflammatory conditions, such as cholecystoenteric fistula, primary sclerosing cholangitis, pancreaticobiliary maljunction, and chronic infection with Salmonella typhi, are also associated with an increased risk of gallbladder cancer.
Therefore we will advice you to obtain the gallbladder removed for your father.
M C Gupta
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